Oxidative decarboxylative synthesis of 2-H-imidazolines from glyoxylic acid and 1,2-diamines.
نویسندگان
چکیده
A novel method to prepare 2-H-imidazolines from glyoxylic acid monohydrate and 1,2-diamines is described; the key reaction of this method is the oxidative decarboxylation of the 2-carboxy imidazolidines by NBS.
منابع مشابه
[Development and application of practical synthetic methods of imidazolines].
This review describes the first method to prepare imidazolines from aldehydes and 1,2-diamines by condensation and successive oxidation using NBS in one-pot operation. The reaction proceeds under mild conditions and can be applied to various aromatic and aliphatic aldehydes and 1,2-diamines. The utility of this method is also demonstrated in the total synthesis of spongotine A and the preparati...
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عنوان ژورنال:
- Chemical communications
دوره 37 شماره
صفحات -
تاریخ انتشار 2008